You have two route choices driving from Houston.  The fast and the slow.  Since most of you are in fast mode, take I-10 west to Fort Stockton, then Highway 67 South to Alpine, then Highway 118 South into Terlingua/Study Butte.

If you don’t want to see the same scenery twice – and you are not in a big hurry – take I-10 west to San Antonio, then Highway 90 to Alpine and then Highway 118 south into Terlingua/Study Butte.  Taking Highway 90 out of San Antonio will take you through more towns and stoplights, but you will get to see Lake Amistad, the Pecos River high bridge and Judge Roy Bean’s former home in Langtry, Texas.  Return home via I-10 east.

If you are driving from Dallas, take I-20 to just west of Odessa, then take either Farm Road 1053 or Highway 18 (from Monahans) south to Fort Stockton. Then Highway 67 South to Alpine and Highway 118 South to Study Butte/Terlingua.

If you are driving from Austin, take Highway 290 through Fredericksburg to I-10; travel west on I-10 to Fort Stockton; take Highway 67 to Alpine, then Highway 118 South to Study Butte/Terlingua.

If you are driving from El Paso, take I-10 east to Van Horn, then Highway 90 to Alpine; then Highway 118 South to Study Butte/Terlingua.

If you are driving from Midland/Odessa, take I-20 to just west of Odessa, then take either Farm Road 1053 or Highway 18 (from Monahans) south to Fort Stockton. Then Highway 67 South to Alpine and Highway 118 South to Study Butte/Terlingua.